Open-Source-Science on Pi Stack

Self-Hosted Crystallography Platforms: Phenix vs CCP4 vs XDS

Thu, 11 Jun 2026 00:00:00 +0000

Introduction

Macromolecular crystallography is the primary method for determining atomic-resolution structures of proteins, nucleic acids, and their complexes. In the era of structural biology and rational drug design, having a self-hosted crystallography pipeline gives research laboratories complete control over their structure determination workflow — from diffraction image processing to model building and refinement.

Self-Hosted Seismic Data Processing: ObsPy vs Madagascar vs Seismic Unix

Thu, 11 Jun 2026 00:00:00 +0000

Introduction

Seismic data processing is a cornerstone of geophysics research, earthquake monitoring, and subsurface exploration. Whether you’re running a university seismology lab, monitoring volcanic activity, or analyzing exploration data, having a self-hosted seismic processing pipeline gives you full control over your data workflow without relying on proprietary software licenses that can cost thousands of dollars per seat.

Self-Hosted Spectroscopic Analysis: Open-Source Raman, FTIR & Spectral Processing Tools

Thu, 11 Jun 2026 00:00:00 +0000

Introduction

Spectroscopic analysis is fundamental to chemistry, materials science, pharmaceutical quality control, and environmental monitoring. From Raman spectroscopy for chemical identification to FTIR (Fourier Transform Infrared) for polymer analysis, spectroscopy generates vast amounts of spectral data that require sophisticated processing, baseline correction, peak fitting, and multivariate analysis.